CAS 89030-95-5: High-Purity Copper Peptide (GHK-Cu) Powder

Product Overview

Copper Peptide (CAS 89030-95-5), scientifically designated as GHK-Cu or Copper Tripeptide-1, is a naturally occurring glycyl-L-histidyl-L-lysine peptide complexed with a copper (II) ion. Characterized by its signature vibrant blue color, GHK-Cu is one of the most celebrated premium ingredients in the high-end cosmetic industry, renowned for its extraordinary biological properties in tissue remodeling, skin barrier repair, intensive anti-aging, and hair follicle stimulation.

We utilize state-of-the-art solid-phase peptide synthesis (SPPS) and purification technologies to manufacture high-purity ($\ge 98.0\%$) GHK-Cu powder, ensuring unmatched stability, solubility, and performance for global cosmetic formulation requirements.

Mechanism of Action (The Three R's of Skin Renewal)

GHK-Cu acts as a powerful signaling and carrier peptide that safely modulates cellular copper intake to drive tissue rejuvenation:

• Extracellular Matrix Remodeling: It actively binds to cell receptors to upregulate the gene expression of collagen, elastin, and glycosaminoglycans (such as hyaluronic acid), shifting the skin into a state of structural repair.

• Fibroblast Activation: It stimulates fibroblasts—the cells responsible for skin elasticity—to proliferate and migrate to areas of micro-damage, accelerating the recovery of compromised skin barriers.

• Anti-Inflammatory & Antioxidant Switch: GHK-Cu suppresses inflammatory cytokines (like TNF-alpha and IL-6) while blocking oxidative damage by activating superoxide dismutase (SOD), making it an elite recovery agent post-aesthetic procedures.

• Hair Care Enhancement: In scalp applications, it enlarges hair follicle size and counteracts follicle shrinking, prolonging the anagen (growth) phase of hair.

Key Benefits & Commercial Advantages

• Superior Anti-Aging Efficacy: Clinically recognized to outpace Vitamin C and Retinoic Acid in accelerating dermal collagen synthesis without causing skin redness or irritation.

• Excellent Post-Procedure Repair: Highly demanded for medical-grade skincare aimed at soothing skin after laser treatments, chemical peels, and microneedling.

• Dual-Applicable Market Potential: Highly versatile across premium face care (anti-wrinkle creams, repair serums) and advanced trichology lines (anti-hair loss essences, scalp treatments).

• Guaranteed Purity & Quality Control: Free from visual impurities or uncomplexed free copper ions, ensuring uniform deep-blue color and excellent patch-test safety profiles.

Formulation & Compatibility Guidelines

CRITICAL COMPATIBILITY ALERT FOR FORMULATORS:

GHK-Cu is highly sensitive to certain cosmetic actives. DO NOT combine GHK-Cu with Chelating Agents (e.g., EDTA), as they will strip the copper ion from the peptide, causing the solution to turn green or clear and completely destroying its efficacy.

Additionally, avoid blending with strong acids (such as High-Concentration L-Ascorbic Acid/Vitamin C, AHA, BHA), as low pH environments ($\le 4.5$) will break the peptide-copper complex.

• Recommended Usage Concentration: 0.05% - 0.2% (for pure powder formulations); 1.0% - 5.0% (for pre-dissolved solutions).

• Solubility: Readily and completely soluble in water.

• Optimum pH Range: Best formulated within a strictly controlled pH 5.5 to 7.0 window.

• Processing Profile: Incorporate during the final cool-down phase of an emulsion or serum base at temperatures below 40°C.

Packaging, Storage & B2B Logistics

• Standard Packaging: Available in 1g, 10g, 50g, 100g, and 1kg high-barrier aluminum bags or secure pharmaceutical-grade amber bottles. Custom bulk configurations can be accommodated.

• Storage Requirement: Protect from light and moisture. For standard manufacturing storage, preserve tightly sealed at -20°C or below.

• Compliance Documentation Available: COA, Material Safety Data Sheet (MSDS), Technical Data Sheet (TDS), and commercial Allergen Statements are instantly provided via our sales team.